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The papers contain correspondence, writings, subject files and personal papers documenting the personal life and writing career of Elizabeth Shepley Sergeant and such subjects as the Taos writers colony, the Indian rights movement, popular psychology, and life in Paris during World War I. Major correspondents include Randolph Bourne, John Collier, Alyse Gregory, Sidney Howard, Haniel Long, Amy Lowell, Mabel Dodge Luhan, and Thornton Wilder.

The papers contain correspondence, memoranda, manuscripts and other papers on the professional career and personal life of psychiatrist and psychoanalyst Trigant Burrow. The papers document Burrow's group laboratory research, the activities of The Lifwynn Foundation, the research of important colleagues like Hans C. Syz and Charles Baker Thompson, and such subjects as doctor-patient and interpersonal relations. The papers include extensive family and personal correspondence, a complete set of Burrow's published writings, drafts of manuscripts, and copies of unpublished and unfinished writings. Major correspondents include Sherwood Anderson, Sigmund Freud, Carl G. Jung, Alfred Korzybski, D. H. Lawrence, Adolf Meyer, Sir Herbert Read, Clarence Shields, and Leo Stein.