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The papers contain extensive documentation of Latourette's personal life, scholarly activities, and involvement in various organizations. Latourette was a professor of missions and Oriental history at Yale University. He held leadership positions in the American Baptist Convention and Foreign Mission Society, American Historical Association, Far Eastern Association, International Committee of Y.M.C.A.'s, Japan International Christian University Foundation, United Board for Christian Colleges in China, World Council of Churches, and Yale-China Association.

The principal figures in these papers are Phillips Foster Greene, a physician and missionary, and his wife, Ruth Altman Greene, a teacher and writer who accompanied her husband during his service of nearly twenty years at the Yale-in-China Medical School in Changsha (1921-1943) and seven years in Rangoon (1951-1958). The papers consist largely of correspondence with family in the United States and with Yale-in-China staff members. The letters are important sources of information on social conditions in China and political events, as well as a record of the Greenes' day-to-day activities. Also in the papers are financial records, newspaper clippings, copies of their articles on life at Changsha, and photographs.