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The Chronological Files relate to the efforts of the Food and Drug Administration to regulate tobacco as a controlled substance. Culled and copied from other FDA files, the series includes clippings, memoranda, reports, and other documents that provide a narrative of the struggle of the FDA and other groups seeking to assign culpability to the tobacco industry for the health hazards of cigarettes and other products. There is considerable topical overlap and duplication with materials in Series I and IV.